AMPHOTERICIN B conventional, 50mg, powder, vial
STD
DINJAMBC5V-
Valid Article
Account code:
60000
HS Code:
300490
Last Updated on:
04/10/2024, 16:22:46
Former
Code(s):
-X DINJAMPH5VC
6.3 - Antifungal medicines
Classification of the medicines in groups and subgroups according to their therapeutic use.
The classification used by MSF is based on the WHO Model List of Essential Medicines.
6.5.2 - Antileishmaniasis medicines
Classification of the medicines in groups and subgroups according to their therapeutic use.
The classification used by MSF is based on the WHO Model List of Essential Medicines.
J02AA01
Anatomical Therapeutic Chemical Classification according to WHOCC
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
AMPHOTERICIN B conventional
Therapeutic Action
Antifungal medicine
Indications
Cryptococcal meningitis (induction phase)
Severe histoplasmosis or penicilliosis
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Instructions for use
Reconstitute the powder vial with 10 ml of water for injection to obtain a concentrated solution at 5 mg/ml amphotericin B.
Dilute the concentrated solution in 500 ml of 5% glucose to obtain a solution at 0.1 mg/ml amphotericin B for slow IV infusion.
The liposomal amphotericin B (AmBisome®) is better absorbed and has less risk of renal toxicity than the conventional amphotericin B (Fungizone®) for the treatment of cryptococcal meningitis.
Precautions for Use
For slow IV infusion, use only 5% glucose (not compatible with other infusion fluids).
Storage
- Powder: between 2ºC and 8°C. In the absence of a refrigerator, can be stored for 7 days maximum below 25°C.
- Concentrated solution (5 mg/ml): keep refrigerated between 2ºC and 8°C for 24hrs maximum. Do not freeze.
- Solution for infusion (0.1 mg/ml): use immediately. Protect from sunlight