ISOSORBIDE DINITRATE, 5mg, sublingual tab.
Valid Article
ISOSORBIDE DINITRATE
Therapeutic Action
Vasodilator, antianginal
Indications
Prophylaxis and treatment of angina pectoris due to coronary artery disease.
Treatment of left-sided or global chronic heart failure in patients with intolerance to angiotensin-converting enzyme (ACE) inhibitors (e.g. enalapril)
Adjunctive therapy in acute heart failure (acute pulmonary oedema)
Not indicated for the relief of accute angina attacks; for an accute attack, use sublingual glyceril trinitrate tablets.
Instructions for use
Chew the tablet and let it melt slowly under the tongue.
For long-term treatment, prefer the prolonged-release formulation to reduce the risk of tolerance and increase patient compliance.
Precautions for Use
To be used in adults only.
Contraindications:
- Hypotension
- Obstructive myocardiopathy (e.g., aortic or mitral stenosis, constrictive pericarditis)
- Intracranial hypertension
- Neurologic injury
- Severe anaemia
Most common side effects: headache, dizziness, fatigue, nausea, tachycardia.
Storage
Below 25ºC - Protect from sunlight - Protect from humidity