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VACCINE YELLOW FEVER, 1 dose, multidose vial

https://medicalguidelines.msf.org/en/node/985
https://unicat.msf.org/cat/product/12430
STD DVACVYEF2VD

Valid Article

Former Code(s): -X DVACZFR0088
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
19.3 - Vaccines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
J07BL01
Anatomical Therapeutic Chemical Classification according to WHOCC
0208
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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VACCINE YELLOW FEVER

CAUTION

The multldose vaccine is worded and codified by unit (= 1 dose) to make the order easier.

Full Name

Synonym: antiamaril vaccine

Therapeutic Action

Freeze-dried vaccine from live-attenuated strain of yellow fever virus

Indications

Prevention of yellow fever in children from 9 months of age and adults living in or travelling to or from endemic areas.

Prevention of yellow fever in mass immunisation campaigns during outbreaks.

Instructions for use

Reconstitute the powder vial with the diluent provided by the manufacturer.

Must be given by IM route into the anterolateral part of the thigh in children < 2 years and into the deltoid muscle in children ≥ 2 years and adults.

Fractional dosing of yellow fever vaccine can only be applied for vials containing 10 doses or less (to reduce the risk of contamination from multiple punctures).

For the multidose vial, do not forget to order the diluent together with the vaccine!

Orders are always done in number of doses and not in number of vials! (See Preliminary remarks on Vaccines)

Precautions for Use

As with all injectable vaccines and/or immunoglobulins, appropriate medical treatment should always be readily available in case of rare anaphylactic reactions following the administration of the product.

Storage

  • Do not freeze.
  • Powder: between 2°C and 8°C - Protect from sunlight
  • Diluent: if not co-packed, a cold chain is not required for storage. However, at least 12 hrs before reconstitution of the vaccine, the diluent must be refrigerated between 2°C and 8°C so that the diluent and powder are at the same temperature (a thermic shock during reconstitution could reduce the vaccine efficacy).
  • Reconstituted vaccine: between 2°C and 8°C, for up to 6 hrs
  • The vaccine vial monitor (VVM) is mandatory on each vaccine.

(Cf Introduction: Thermosensitive products)