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ETHIONAMIDE, powder, 5 g [Sigma-E6005.5G]
STD
SASTAPWDETI5
Valid Article
Account code:
60200
HS Code:
382290
Last Updated on:
21/11/2024, 22:47:33
Former
Code(s):
-X SLASETHN5P- SLASZNL0083
W0104010699 - Media for mycobacteria cultures - manual & automated (for ast drugs , supplements) - other
European Medical Device Nomenclature (EMDN) is the nomenclature of use by manufacturers when registering their medical devices in the EUDAMED database. EMDN is characterised by its alphanumeric structure that is established in a seven-level hierarchical tree.
OC subscriptions: included in supply or field order tools (e.g. UniField)
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SC subscriptions: included in supply or field tools
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OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)
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ETHIONAMIDE
Reserved for TB culture programmes.
Definition
Antimycobacterial used for drug susceptibility testing of M. tuberculosis complex.
Synonym
2-Ethyl-4 pyridinecarbothioamide
Specifications
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Technical specifications
- Yellow powder
- White to off-white, in solution colourless to faint yellow
- Clear yellow solution at 50 mg/ml in Pyridine
- C8H10N2S
- Mocecular weight: 166.24 g/mol
- CAS No: 536-33-4
Packaging & Labelling
5 g in glass vial
Transport not regulated
Instructions for use
- For the procedure of stock solution and working solution preparations, refer to Tuberculosis Culture Laboratory, MSF-ITM, 2014.
- The drug working solution is added to the medium during preparation (agar or LJ) or prior to inoculation (MGIT broth tubes).
- Avoid contact with skin and eyes.
Storage
- Keep refrigerated between 2º C and 8º C. Do not freeze
- Keep container tightly closed in a dry and well-ventilated place.
- Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed
Waste management
Substance with hazardous characteristics. Please contact your watsan referent for advice on proper disposal.
Detailed hazard and precautionary information can be found in the safety data sheet (SDS).
Classification EC Regulation N° 1272/2008
- Acute toxicity, Oral: Category 4, H302
- Reproductive toxicity: Category 2, H361
Signal Word
Warning
| H302 | Harmful if swallowed |
| H361 | Suspected of damaging fertility or the unborn child (route of exposure if it is conclusively proven that no other routes of exposure cause the hazard). |
| P202 | Do not handle until all safety precautions have been read and understood. |
| P270 | Do not eat, drink or smoke when using this product. |
| P264 | Wash … thoroughly after handling |
| P280 | Wear protective gloves/protective clothing/eye protection/face protection |
| P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician if you feel |
| P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
MSF requirements
Ethionamide is part of the second line drugs used against M. tuberculosis complex. The test is performed to investigate resistance of the mycobacteria to this antibiotic. It can be used for liquid and solid cultures.
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