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ISONIAZID, powder, 5 g [Sigma-Fluka-I3377]

https://unicat.msf.org/cat/product/18795
STD SASTAPWDINH5

Valid Article

Former Code(s): SLASISON5P-
Single use
A single-use device, also referred to as a disposable device, is intended for use on one patient during a single procedure. It is not intended to be reprocessed (i.e., cleaned and disinfected or sterilized).
W0104010699 - Media for mycobacteria cultures - manual & automated (for ast drugs , supplements) - other
European Medical Device Nomenclature (EMDN) is the nomenclature of use by manufacturers when registering their medical devices in the EUDAMED database. EMDN is characterised by its alphanumeric structure that is established in a seven-level hierarchical tree.
P
The order of this product needs to be justified and is only acceptable under certain conditions.
CT25
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ISONIAZID

Reserved for TB culture programmes.

Definition

Antimycobacterial used for drug susceptibility testing of M. tuberculosis complex.

Synonym

Isonicotinic acid hydrazide, INH Isonitinic hydrazide

Specifications

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Technical specifications

  • White powder
  • Soluble in water
  • Formula : C6H7N3O
  • Purity : >= 99%
  • CAS number: 54-85-3
  • Molecular weight: 137,14 g/mol

Packaging & Labelling

5 g in glass vial

Transport not regulated

Instructions for use

For the procedure of the stock solution and working solution preparations, refer to Tuberculosis Culture Laboratory, MSF-ITM, 2014.

Avoid contact with skin and eyes.

Storage

  • Store in a cool place
  • Keep container tightly closed in a dry and well-ventilated place
  • Avoid formation of dust and aerosols
  • Provide appropriate exhaust ventilation at places where dust is formed

Waste management

Substance with hazardous characteristics. Please contact your watsan referent for advice on proper disposal.

Detailed hazard and precautionary information can be found in the safety data sheet (SDS).

Classification EC Regulation N° 1272/2008

  • Acute toxicity, Oral : Category 4, H302
  • Skin irritation : Category 2, H315
Image

Signal Word

Warning

H302Harmful if swallowed
H315Causes skin irritation
P264Wash … thoroughly after handling
P280Wear protective gloves/protective clothing/eye protection/face protection
P301 + P312IF SWALLOWED: call a POISON CENTER or doctor/physician if you feel
P302 + P352IF ON SKIN: wash with plenty of soap and water
P332 + P313If skin irritation occurs: get medical advice/attention
P362 + P364Take off contaminated clothing and wash it before reuse.

MSF requirements

Isoniazid is one of the first line drugs used against M. tuberculosis complex. The test is performed to investigate resistance of the mycobacterium to this antibiotic. The drug solution is added to agar or egg-based media during preparation.

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