KANAMYCIN sulfate, powder, 1 g [Sigma-K1377-1G]
NST
SASTAPWDKAN1
Valid Article
Account code:
60200
Last Updated on:
03/11/2022, 15:11:58
Former
Code(s):
SLASKANA1-- SASTAPWD1--
KANAMYCIN
Article became NST in 2021 - No longer part of the drug susceptibility testing of M. tuberculosis complex.
Reserved for TB culture programmes.
Definition
Antimycobacterial used for drug susceptibility testing of M. tuberculosis complex.
Specifications
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Technical specifications
- Powder
- White to Off-White, in solution colorless to faint yellow
- Soluble in water
- Formula: C18H36N4O11.H2O4S
- Purity: ≥ 750µg per mg
Packaging
1 g in glass bottle
Transport not regulated
Instructions for use
- Avoid exposure - obtain special instructions before use.
- For the procedure of stock solution and working solution preparations, refer to Tuberculosis Culture Laboratory, MSF-ITM, 2014.
- The drug working solution is added to the medium during preparation (agar or LJ) or prior to inoculation (MGIT broth tubes).
Storage
- Store powder at room temperature
- Prepared solutions are stable for 5 days at 37°C
- Aqueous stock solutions can be stored at 2-8 °C
- Keep container tightly closed in a dry and well-ventilated place
- Avoid formation of dust and aerosols
- Provide appropriate exhaust ventillation at places where dust is formed
Classification EC Regulation N° 1272/2008
- Reproductive toxicity: Category 1B, H360
Signal Word
Danger
H360 | May damage fertility or the unborn child (state specific effect if known) (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
P201 | Obtain special instructions before use. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
MSF requirements
Kanamycin is part of the second line drugs used against M. tuberculosis complex. The test is performed to investigate resistance of the mycobacteria to this antibiotic. It can be used for liquid and solid cultures.
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