RIFAMPICIN, powder, 1 g [Sigma-R3501-1G]
Valid Article
RIFAMPICIN
Reserved for TB culture programmes.
Definition
Antimycobacterial used for drug susceptibility testing of M. tuberculosis complex.
Synonym: 3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP.
Synonym
3-(4-Methylpiperazinyliminomethyl)rifampicin SV, Rifampicin AMP
Specifications
Technical specifications
- Crystalline red powder
- Easily soluble in methyl chloride, dimethyl sulfoxyde and chloroform, soluble in ethyl acetate and in methanol. Slightly soluble in water (pH less than 6)
- Formula: C43H58N4O12
- Purity: 97%
- Molecular weight: 822.94 g/mol
Packaging & Labelling
1 g or 5 g in glass vial
Transport not regulated
Instructions for use
For the procedure of stock solution and working solution preparations, refer to Tuberculosis Culture Laboratory, MSF-ITM, 2014.
Storage
- Recommended storage temperature -20°C
- Store in tight, light-resistant container
Waste management
Substance with hazardous characteristics. Please contact your watsan referent for advice on proper disposal.
Detailed hazard and precautionary information can be found in the safety data sheet (SDS).
Classification EC Regulation N° 1272/2008
- Acute toxicity, Category 4, H302
Signal Word
Warning
H302 | Harmful if swallowed |
P270 | Do not eat, drink or smoke when using this product. |
P264 | Wash … thoroughly after handling |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician if you feel |
P501 | Dispose of contents/container to location in accordance with local and regional/ national/ international regulations |
MSF requirements
Rifampicin is the key antibiotic of the first line drugs used against M. tuberculosis complex. The test is performed to investigate resistance of the mycobacterium to this antibiotic. The drug solution is added to agar or egg-based media during preparation.