TUBERCULIN, 5 TU/0.1ml, multidose, 1 dose, vial.
Valid Article
TUBERCULIN 5 TU/0.1 ml
CAUTION
This test is worded and codified by unit to make the order easier, but it is always packaged in vial of 15 doses.
Full Name
Synonym: Mantoux-test
Therapeutic Action
Purified tuberculin protein derivative
Biologic diagnostic agent
Indications
Testing for a tuberculin hypersensitivity reaction
Screening for tuberculosis bacilli infection
Pre- or post-vaccination test of the BCG vaccine
This test is used to diagnose tuberculosis infection :
- in children in high-prevalence countries, and especially in the close vicinity of contagious cases, provided that a chest X-ray can be performed.
- in international staff who have already been tested in order to detect a tuberculin conversion indicating a recent infection, and to propose a preventive treatment (after elimination of active tuberculosis).
Instructions for use
Specifications:
- Recommended dose: 0.1 ml = 5 TU (Tuberculin Units) = 0.04 µg tuberculin
- Positive threshold: 6 mm
- Good concordance of induration diameters with the tuberculin reference OMS-RT23
- Sensitivity in comparison with OMS-RT23: 95.4%
- Specificity in comparison with OMS-RT23: 95.7%
Method of administration
Must be given by intradermal injection on the anterior face of the forearm.
Use a 1 ml graduated 1/100 syringe and a needle Luer 26 G (0.45 x 13 mm), brown, ID.
Evaluation of the test
The result should be evaluated approximately 3 days (72 hrs) after the injection. It should always be interpreted in the medical context.
The reaction to the test is an induration, usually accompanied by erythema.
Only the induration is used for the interpretation of the test (any erythema is disregarded). The clearly palpable induration should be measured in millimetres (mm) in its widest diameter (with a transparent flexible ruler).
The reaction is considered positive if the diameter of the induration is 6 mm or greater. A phlyctenular reaction is considered highly positive.
Precautions for Use
Immediate erythematous reaction may occur at the injection site. Vesiculation, ulceration or necrosis may appear in highly sensitive persons.
Storage
- Keep refrigerated between 2ºC and 8ºC. - Protect from sunlight
- Do not freeze.
- After opening, use the vial within 24 hrs.