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LPV 40mg / r 10mg, pellets-in-a-capsule

https://medicalguidelines.msf.org/en/node/433
https://unicat.msf.org/cat/product/65475
NST DORALPVR1P-

Valid Article

Former Code(s): DORALPRF1C- DORALPVR1C-
Article is intended to be used with children (<12 years) ONLY.
6.4.2.3 - Protease inhibitors
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
J05AR10
Anatomical Therapeutic Chemical Classification according to WHOCC
S
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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LOPINAVIR (LPV) / RITONAVIR (r)

Therapeutic Action

Fixed-dose combination (FDC) of two antiretrovirals, protease inhibitors (PI)

Indications

HIV infection, in combination with other antiretrovirals

Instructions for use

Granules in sachet and 100mg/25mg tablets are intended for paediatric use.

Pour the granules into a small amount of breast milk, water or soft foods and administer immediately (within 2 hours of preparation max.).

Precautions for Use

Pellets-in-a-capsule and oral solutions became non-standard according to 2021 WHO list for antiretroviral drugs for children:

  • granules in sachet can be given to children from the age of two weeks (instead of three months) and are easier to administer than pellets in capsule.
  • with increasing use of integrase inhibitor–based regimens and a preference for granules, oral solution should no longer be required.

Storage

Below 25ºC - Protect from sunlight - Protect from humidity