ENTECAVIR, 0.5mg, tab.

NST DORAENTE5T-

Valid Article

Article is intended to be used with children (<12 years) ONLY.
6.4.4.1 - Medicines for hepatitis B
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ENTECAVIR (ETV)

Therapeutic Action

Antiretroviral, nucleotide reverse transcriptase inhibitor (NRTI)

Indications

Chronic hepatitis B virus (HBV) infection in adults with impaired renal function and children from 2 to 12 years of age.

Instructions for use

Must be taken on an empty stomach (more than 2 hours before and more than 2 hours after a meal).

Tenofovir disoproxil fumarate (TDF), another antiretroviral NRTI, is recommended as first-line treatment for chronic hepatitis B virus infection in adults and children from 12 years of age.

Precautions for Use

Administer with caution in patients with renal impairment. Closely monitor renal function .

The most common side effects include headache, fatigue, dizziness, and nausea.

Spontaneous exacerbations in chronic hepatitis B are relatively common and are characterised by transient increases in serum ALT.

Storage

Below 25ºC - Protect from sunlight