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CARVEDILOL, 3.125mg, breakable tab.

https://unicat.msf.org/cat/product/76807
STD DORACARV3TB

Valid Article

Article is intended to be used with children (<12 years) ONLY.
12.4 - Medicines used in heart failure
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
C07AG02
Anatomical Therapeutic Chemical Classification according to WHOCC
M
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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CARVEDILOL

Therapeutic Action

Vasodilatory non-selective beta-blocker

Indications

Chronic heart failure (mild to severe) in adults and children.

Left ventricular dysfunction following myocardial infarction in clinically stable patients.

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Instructions for use

Tablets should be taken with sufficient fluid.

Dosage:

  • Heart failure:
    • Adults: start at 3.125 mg twice daily and increase to 6.25, 12.5, and then 25 mg twice daily over intervals of at least 2 weeks. Maintain lower doses if higher doses are not tolerated.
    • Children: start at 0.05 mg/kg (max 3.125 mg) twice daily and increase to 0.1, 0.2, and then 0.35 mg/kg twice daily (max 25 mg) over intervals of at least 2 weeks. Maintain lower doses if higher doses are not tolerated
  • Left ventricular dysfunction following myocardial infarction:
    • start at 6.25 mg twice daily and increase to 12.5 mg then 25 mg twice daily after intervals of 3 to 10 days. A lower starting dose or slower titration may be used.

Precautions for Use

Beta-blockers are contraindicated in :

  • cardiogenic shock or decompensated heart failure (acute heart failure) requiring the use of diuretics or IV inotropic therapy.
  • bronchial asthma or related bronchospastic conditions
  • second-or third-degree AV block
  • sick sinus syndrome
  • severe bradycardia (unless permanent pacemaker in place)
  • severe hepatic impairment.

Storage

Below 25ºC - Protect from sunlight