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  3. MISOPROSTOL, 25µg, vaginal tab.
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MISOPROSTOL, 25µg, vaginal tab.

https://medicalguidelines.msf.org/en/node/443
https://unicat.msf.org/cat/product/94299
STD DEXTMISP25TV

Valid Article

22.3 - Uterotonics
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
G02AD06
Anatomical Therapeutic Chemical Classification according to WHOCC
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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MISOPROSTOL 25µg

Therapeutic Action

Oxytocic compound, synthetic analogue of prostaglandin

Indications

Induction of labour

Instructions for use

May be given by oral or vaginal route:

  • If oral administration is not possible (vomiting, impaired consciousness), administer by vaginal route.
  • Caution! oral tablet (DORAMISP25T) may be administered by oral or vaginal route. In contrary, vaginal tablet (DEXTMISP25TV) must be administered by vaginal route only!
  • Administration by vaginal route:
    • to be administered by medical staff (doctor or midwife)
    • wash hands carefully.
    • take the tablet out from the blister.
    • the patient laying down on a gynaecological examination table, insert the tablet into the posterior fornix of the vagina.

Misoprostol 200 µg can be used as an alternative in case of supply issue with 25 µg dosage. Dissolve 1 tablet of misoprostol 200 µg in 200 ml water and give 25 ml of the dissolved solution (25 ml = 25 µg).

Precautions for Use

  • Do not administer in the event of previous caesarean section.
  • Administer with caution in case of grand multiparity or overdistention of the uterus (risk of uterine rupture).
  • Monitor the intensity and frequency of contractions as well as foetal heart rate after administration of misoprostol.
  • Do not administer simultaneously with oxytocin.
  • Do not use misoprostol in ectopic or molar pregnancy.

Storage

Below 25ºC - Protect from sunlight -Protect from humidity