ATRACURIUM besilate, 10mg/ml, 2.5ml, amp.

STD DINJATRB2A-

Valid Article

Former Code(s): DINJATRB1A-
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
20 - Muscle relaxants (peripherally-acting) and cholinesterase inhibitors
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
M03AC04
Anatomical Therapeutic Chemical Classification according to WHOCC
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ATRACURIUM besilate

Therapeutic Action

Neuromuscular blocking agent (NMBA), non-depolarising, with an intermediate onset and duration of action.

Indications

Maintenance of neuromuscular block during surgery.

In critical care, NMBAs are used in specific indications: intubation, mechanical ventilation of ARDS acute respiratory distress syndrome, acute asthma exacerbation, tetanus.

Atracurium can be considered as second choice non-depolarizing NMBA in projects where there is a substantial medical need to account for hepatic or kidney function.

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Instructions for use

Must be given as IV injection or continuous IV infusion.

Systematically order neostigmine together with atracurium.

Systematically order the corresponding pre-printed label to identify the syringe containing the product.

Atracurium can be used as an alternative to vecuronium, when vecuronium cannot be imported or used.

Precautions for Use

Atracurium requires cold chain for transport and storage, it is essential to ensure that a properly functioning cold chain is in place before ordering.

Caution concerning neuromuscular blocking agents (NMBAs)!

  • NMBAs are high-risk medications: paralysing agent that may cause respiratory distress.
  • NMBAs must only be administered in environments with equipment and monitoring for advanced airway respiratory support.
  • Syringes containing a NMBA must be identified with a standard pre-printed label corresponding to the product.
  • If not needed, the NMBA must be disposed accordingly.

Storage

  • Between 2ºC and 8ºC - Protect from sunlight
  • Do not freeze.
  • After opening the ampoule, use the product immediately.
  • Discard any unused solution.

(Cf Introduction: Thermosensitive products)