MIDAZOLAM, 1mg/ml, 5ml, amp
Valid Article
MIDAZOLAM, 1mg/ml, 5ml, amp
Therapeutic Action
Short-acting hypnotic and sedative with anxiolytic, anticonvulsant and muscle relaxant effect.
Derivative of the benzodiazepine group
Indications
Sedation of adult and paediatric patients as a component of anaesthesia or during treatment in a critical care setting.
First-line treatment for seizures in children, administered by buccal or intranasal route when IV access with diazepam is not possible.
First-line treatment for seizures in adults, administered by IM, IV, or intranasal route.
Management of patients with acute severe agitation or severe behavioural disturbance in emergency settings.
- See: Perioperative management of surgical/trauma pain, MSF, 2024
- See: Essential drugs, MSF, 2024
- See: Local Anaesthetic Systemic Toxicity, MSF protocol, 2021
- See: Paediatric care - Clinical and therapeutic guidelines, MSF, 2024
- See: Standards for paediatric procedural sedation, MSF, 2021
- See: Management of Seizure GCSE Adults MSF 2024
Instructions for use
For intranasal administration in children, it is recommended to use a mucosal atomization device.
Midazolam should only be administered by personnel specifically trained in the detection and management of airway obstruction, hypoventilation and apnoea, including maintenance of cardiopulmonary function, and with experience in cardiovascular resuscitation.
A benzodiazepine reversal agent (flumazenil DINJFLUM1A) should be immediately available during the administration of midazolam.
Systematically order the corresponding pre-printed label to identify the syringe containing the product (see related articles)
Distribution to be controlled: narcotics register or supervision of amounts in and out, and storage under lock and key. (Cf Introduction: Narcotic and psychotropic medicines under international control).
Precautions for Use
Caution! Do not confuse with the 5mg/ml midazolam concentration, which is reserved for continuous IV infusion in intensive care units.
Storage
- Below 25ºC - Protect from sunlight
- After opening the ampoule, use the product immediately.