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PENTAMIDINE isetionate, 300mg, powder, vial

https://medicalguidelines.msf.org/en/node/908
https://unicat.msf.org/cat/product/11778
STD DINJPENT3V-

Valid Article

Former Code(s): -X DINJZFR0194
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
6.5.4 - Antipneumocystosis and antitoxoplasmosis medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
6.5.5.1 - African trypanosomiasis
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
P01CX01
Anatomical Therapeutic Chemical Classification according to WHOCC
P
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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PENTAMIDINE

Therapeutic Action

Antiprotozoal active against Pneumocystis jiroveci (carinii), antitrypanosomal

Indications

Second-line treatment of pneumocystis, in case of intolerance or contraindications to sulfamethoxazole-trimethoprim (cotrimoxazole).

Early phase of Human African Trypanosomiasis

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Instructions for use

Reconstitute the powder vial with 10 ml of water for injection.

The reconstituted solution must be given as deep IM injection or IV infusion in 250 ml of 5% glucose.

1 mg pentamidine isétionate is equivalent to 0.57 mg pentamidine base.

300 mg pentamidine isetionate (1 vial) is equivalent to 172.4 mg pentamidine base.

Pentamidine is preferred to suramin (risk of major side effects in filariasis endemic areas).

Storage

  • Below 25°C - Protect from sunlight
  • After reconstitution, keep the solution refrigerated between 2°C and 8°C for a maximum of 24 hrs.