VACCINE HEPATITIS B, adult, 1 dose, multidose vial


Valid Article

The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
19.3 - Vaccines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
Anatomical Therapeutic Chemical Classification according to WHOCC
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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The multidose vaccines are worded and codified by unit (= 1 dose) to make the order easier.

Therapeutic Action

Recombinant, hepatitis B surface antigen (HBsAg) (purified), adsorbed vaccine


Active immunisation against infection caused by hepatitis B virus.

The multidose presentation is intended for vaccination of :

  • newborns in maternity wards
  • staff or teams if the number of people to be vaccinated is high (> 5 people)
  • persons treated for sexual violence if the number of people to be vaccinated is high (> 5 persons)

Remark: Never hesitate to open a vial even if there is only one eligible person to be vaccinated and only multi-dose vials are available.

Orders are always done in number of doses and not in number of vials! (See Preliminary remarks on Vaccines)

The single-dose (monodose) presentation is intended for specific contexts where consumption is very low.

Vaccine sometimes supplied by the Ministry of Health of the country concerned.

Instructions for use

Suspension in liquid form

Shake the vial before use to homogenise the suspension.

Must be given by IM route into the anterolateral aspect of the thigh (in infants) or the deltoid muscle.

Dosage varies according to age and the vaccine used. Follow the manufacturer's instructions.
Children: one dose = 5 to 10 micrograms
Adults: one dose = 10 to 20 micrograms

Follow the national immunisation schedule, or if not available, the WHO schedule.

Precautions for Use

As with all injectable vaccines and/or immunoglobulins, appropriate medical treatment should always be readily available in case of rare anaphylactic reactions following the administration of the product.


  • Keep refrigerated between 2ºC and 8ºC - Protect from sunlight
  • Do not freeze.
  • For multidose vials, refer to the WHO policy on the use of opened vials of vaccine.

(Cf Introduction: Thermosensitive products)