VACCINE RABIES, CCV, cell culture, monodose, vial + diluent
Valid Article
VACCINE RABIES
Therapeutic Action
Freeze-dried vaccine containing inactivated rabies virus.
Vaccine prepared from cell cultures in embryonated eggs or purified cells (CCEEVs):
- human diploid-cells (HDCV)
- purified Vero-cells (PVRV)
- purified chick embryo-cells (PCEC)
Indications
Pre-exposure prophylaxis for anyone living in an isolated area where rabies risk is present and/or in a high risk area.
Post-exposure prophylaxis for anyone bitten by a suspect animal after assessment by a medical doctor.
Instructions for use
Reconstitute the powder vial with the diluent supplied by the manufacturer.
Must be given by IM route.
For the vaccine monodose (without diluent), do not forget to order the diluent together with the vaccine!
The different CCEEV vaccines can be used interchangeably without any safety problems or loss of efficacy.
Precautions for Use
Do not administer into the gluteal muscle.
Avoid the use of vaccines prepared from animal nerve tissue (NTVs): they are less immunogenic than CCEEV vaccines and can induce severe adverse reactions.
As with all injectable vaccines and/or immunoglobulins, appropriate medical treatment should always be readily available in case of rare anaphylactic reactions following the administration of the product.
Storage
- Do not freeze.
- Powder: between 2°C and 8°C - Protect from sunlight
- Diluent: if not co-packed, cold chain is not required for storage. However, at least 12 hrs before reconstitution of the vaccine, the diluent must be refrigerated between 2°C and 8°C so that the diluent and lyophilised powder are at the same temperature (a thermic shock during reconstitution would reduce the vaccine efficacy).
- Reconstituted vaccine: use immediately.