AMPHOTERICIN B SUPPL, powder, 250mg [Sigma-A9528-250MG]

STD SBCMSUPPAH250

Valid Article

Former Code(s): SLASAMPH250
Single use
A single-use device, also referred to as a disposable device, is intended for use on one patient during a single procedure. It is not intended to be reprocessed (i.e., cleaned and disinfected or sterilized).
W0104010699 - Media for mycobacteria cultures - manual & automated (for ast drugs , supplements) - other
European Medical Device Nomenclature (EMDN) is the nomenclature of use by manufacturers when registering their medical devices in the EUDAMED database. EMDN is characterised by its alphanumeric structure that is established in a seven-level hierarchical tree.
The order of this product needs to be justified and is only acceptable under certain conditions.
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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AMPHOTERICIN B

Reserved for TB culture programmes.

Definition

Antifungal antibiotic added in culture media to inhibit fungal growth.

Synonym

Fungizone, AmBisome

Specifications

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Technical specifications

  • Yellow to orange powder
  • Formula: C47H73NO17
  • Purity: 80%
  • Soluble in DMSO, insoluble in water

Packaging & Labelling

Plastic bottle

Transport not regulated

Instructions for use

To prepare 800 μg/ml stock solutions

  • dissolve amphotericin B in DMSO (dimethyl sulphoxide)
  • then add water
  • filter the mixture before preparing the aliquots
StS = Stock solution ampho
Ratio Vol StS : Vol 7H11800µl/200 ml
CCStS1mg/ml
CCStS1µg/µl
Weight of Ampho / 200 ml 7H11800µg
Petri dishes / 200 ml 7H118dishes
Weight of Ampho / dish100µg
Dish / 100 mg ampho1000dishes

Storage

  • Keep refrigerated between 2º C and 8º C
  • Protect from light and humidity.
  • Stock solutions stored between +2ºC and +8°C are stable for up to 1 month. For long terms, store at –20°C.
  • Shelf life: 5 years

(Cf Introduction: Thermosensitive products)

Classification EC Regulation N° 1272/2008

  • kin irritation: Category 2, H315
  • Eye irritation: Category 2, H319
  • Specific target organ toxicity - single exposure: Category 3, H335
Image

Signal Word

Warning

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305 + P351 + P338IF IN EYES: rinse cautiously with water for several minutes. If the victim wears contact lenses, remove them if possible. Keep rinsing

MSF requirements

Antifungal antibiotic used to decrease fungal contamination of Middlebrook 7H11 agar plates used for Thin Layer Agar technique.

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