IMMUNOGLOBULIN HUMAN anti-D, 300µg, syr.
Valid Article
IMMUNOGLOBULIN HUMAN anti-D
Therapeutic Action
Anti-D (Rh) immunoglobulin contains specific antibodies (IgG) against the Rh(D) antigen of human erythrocytes.
Indications
Instructions for use
One ml contains 150 micrograms (750 IU) human anti-D immunoglobulin.
Must be given by slow IV or IM injection.
The dose of anti-D immunoglobulin should be determined according to the level of exposure to Rh(D)-positive red blood cells (RBCs) and based on the knowledge that 0.5 ml of Rh(D)-positive RBCs or 1 ml of Rh(D)-positive blood is neutralised by approximately 10 micrograms (50 IU) of anti-D immunoglobulin.
Precautions for Use
Anti-D immunoglobulin is intended for maternal administration. Do not administer to the new-born infant.
Do not administer in Rh(D) positive individuals, nor in individuals already immunised to Rh(D) antigen.
As with all injectable vaccines and/or immunoglobulins, appropriate medical treatment should always be readily available in case of rare anaphylactic reactions following the administration of the product.
Storage
- Pre-filled syringe: keep refrigerated between 2ºC and 8ºC - Protect from sunlight
- Powder + diluent: below 25°C - Protect from sunlight
- Do not freeze.