VECURONIUM bromide, 10mg, powder, vial
Valid Article
VECURONIUM
Therapeutic Action
Neuromuscular blocking agent (NMBA), non-depolarising, with an intermediate onset and duration of action.
Indications
Maintenance of neuromuscular block during surgery.
In critical care, NMBAs are used in specific indications: intubation, mechanical ventilation of ARDS acute respiratory distress syndrome, acute asthma exacerbation, tetanus.
Vecuronium is considered as second choice non-depolarizing NMBA. It can be used an an alternative to rocuronium (first-choice non-depolarizing NMBA) in case of supply issue or import constraints with rocuronium.
Instructions for use
Reconstitute the powder vial with 5 ml of water for injection.
The reconstituted solution must be given as IV injection (bolus) or continuous IV infusion.
Systematically order neostigmine together with vecuronium.
Systematically order the corresponding pre-printed label to identify the syringe containing the product.
Rocuronium has a better profile than vecuronium as it allows to be used in the two scenarios : induction in rapid sequence and maintenance of neuromuscular block.
Precautions for Use
Vecuronium solution is not compatible with thiopental solution. Flush the tube before injecting vecuronium.
Caution concerning neuromuscular blocking agents (NMBAs)!
- NMBAs are high-risk medications: paralysing agent that may cause respiratory distress.
- NMBAs must only be administered in environments with equipment and monitoring for advanced airway respiratory support.
- Syringes containing a NMBA must be identified with a standard pre-printed label corresponding to the product.
- If not needed, the NMBA must be disposed accordingly.
Storage
- Below 25ºC
- After reconstitution, use the solution immediately.
- Discard any unused solution.