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ROCURONIUM bromide, 10mg/ml, 5ml, vial

https://unicat.msf.org/cat/product/79813
STD DINJROCU5V-

Valid Article

Former Code(s): DINJOCBZLB0016
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
20 - Muscle relaxants (peripherally-acting) and cholinesterase inhibitors
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
M03AC09
Anatomical Therapeutic Chemical Classification according to WHOCC
0208
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ROCURONIUM bromide

Therapeutic Action

Non-depolarizing neuromuscular blocking agent (NMBA) with a rapid to intermediate onset and an intermediate duration of action.

Indications

Maintenance of neuromuscular blockade during surgery.

Rapid Sequence Induction (RSI) of anaesthesia.

In critical care, NMBAs are used for specific indications such as intubation, mechanical ventilation in Acute Respiratory Distress Syndrome (ARDS), acute asthma exacerbation, tetanus.

Rocuronium should be considered as the first choice non-depolarizing NMBA.

Instructions for use

The solution must be clear and free of visible particles.

Must be given as IV injection (bolus) or continuous IV infusion

Systematically order neostigmine together with rocuronium.

Systematically order the corresponding pre-printed label to identify the syringe containing the product.

Rocuronium has a better profile than vecuronium, as it is suitable for both rapid sequence induction and maintenance of neuromuscular block.

Rocuronium can be used as an alternative to suxamethonium (succinylcholine) in cases of critical shortage or medical contraindication. In such cases, dosages should be adjusted accordingly (risk of prolonged neuromuscular block with rocuronium). Contact your anaesthesia advisor for more details.

Precautions for Use

Caution with Neuromuscular Blocking Agents (NMBAs):

  • NMBAs are high-risk medications: paralysing agent that may cause respiratory distress.
  • They should only be administered in hospital settings by personnel experience with their use.
  • Equipment for tracheal intubation and advanced airway assistance must be immediately available.
  • Syringes containing an NMBA must be identified with a standard pre-printed label corresponding to the product.
  • If not needed, the NMBA must be disposed of appropriately.

Storage

  • Keep refrigerated between 2ºC and 8ºC.
  • Note: Rocuronium manufactured by Fresenius no longer requires a cold chain. Always refer to the manufacturer's instructions on the packaging.
  • After opening the vial, use the product immediately.
  • Discard any unused solution.