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ROCURONIUM bromide, 10mg/ml, 5ml, vial

https://unicat.msf.org/cat/product/79813
STD DINJROCU5V-

Valid Article

Former Code(s): DINJOCBZLB0016
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
20 - Muscle relaxants (peripherally-acting) and cholinesterase inhibitors
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
M03AC09
Anatomical Therapeutic Chemical Classification according to WHOCC
0208
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ROCURONIUM bromide

Therapeutic Action

Neuromuscular blocking agent (NMBA), non-depolarising, with an intermediate to rapid onset and intermediate duration of action.

Indications

Maintenance of neuromuscular block during surgery.

Rapid Sequence Induction (RSI) of anesthesia.

In critical care, NMBAs are used in specific indications: intubation, mechanical ventilation of ARDS acute respiratory distress syndrome, acute asthma exacerbation, tetanus.

Rocuronium should be considered as first choice non-depolarisng NMBA.

Instructions for use

Must be given as IV injection (bolus) or continuous IV infusion

Systematically order neostigmine together with rocuronium.

Systematically order the corresponding pre-printed label to identify the syringe containing the product.

Rocuronium has a better profile than vecuronium as it allows to be used in the two scenarios : induction in rapid sequence and maintenance of neuromuscular block.

Rocuronium can be used as an alternative to suxamethonium (succinylcholine) in case of critical shortage or medical contraindication. In that case, dosages should be adapted accordingly (risk of prolonged neuromuscular block with rocuronium). Contact your anaesthesia advisor for more details.

Precautions for Use

Rocuronium requires a cold chain for transport and storage. It is essential to ensure that a properly functioning cold chain is in place before ordering.

Caution concerning neuromuscular blocking agents (NMBAs)!

  • NMBAs are high-risk medications: paralysing agent that may cause respiratory distress.
  • NMBAs must only be administered in environments with equipment and monitoring for advanced airway respiratory support.
  • Syringes containing a NMBA must be identified with a standard pre-printed label corresponding to the product.
  • If not needed, the NMBA must be disposed accordingly.

Storage

  • Keep refrigerated between 2ºC and 8ºC
  • After opening the vial, use the product immediately.
  • Discard any unused solution.

(Cf Introduction: Thermosensitive products)