HYDROXYCARBAMIDE, 500mg, caps.

STD DORAHYDC5C-

Valid Article

10.3 - Other medicines for haemoglobinopathies
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
L01XX05
Anatomical Therapeutic Chemical Classification according to WHOCC
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
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OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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HYDROXYCARBAMIDE

Full Name

Hydroxycarbamide (Hydroxyurea)

Therapeutic Action

Antineoplastic antimetabolite increasing the production of foetal haemoglobin, which decreases the sickling of erythrocytes, reducing the frequency of painful crisis and the need for blood transfusions in sickle cell patients.

Indications

Prevention of recurrent painful vaso-occlusive crises including acute chest syndrome in adults, adolescents and children over 2 years of age with symptomatic Sickle Cell Syndrome

Instructions for use

Precautions for Use

Contraindicated in case of severe anaemia.

Monitor closely the haematological status, renal and hepatic functions.

Administer with caution in patients with mild to moderate renal impairment.

Storage

Below 25°C - Protect from sunlight - Protect from humidity