ARTESUNATE 60mg, powder,vial +NaHCO3 5% 1ml +NaCl 0.9% 5ml
Valid Article
ARTESUNATE
Therapeutic Action
Antimalarial, artemisinine derivative
Indications
Severe malaria caused by Plasmodium falciparum
Instructions for use
Combi-pack containing two necessary diluents:
- 1 powder vial of 60 mg artesunate
- 1 ampoule containing 1 ml of 5% sodium bicarbonate (NaHCO3) for reconstitution
- 1 ampoule containing 5 ml of 0.9% NaCl for dilution
Refer to the instructions detailed in GUIDELINES FOR ADMINISTRATION OF INJECTABLE ARTESUNATE FOR SEVERE MALARIA (see articles related) for reconstitution, dilution and administration.
ARTESUNATE 60mg, powder,vial + NaHCO3 5% 1ml + NaCl 0.9% 5ml (DINJARTS6V-) and ARTESUNATE 60mg, pwd vial + ARGININE 2%/NaHCO3 0.84% 3ml (DINJARTS6V3) are interchangeable and weight-dosing is the same. Missions should progressively shift from DINJARTS6V- to DINJARTS6V3.
Must be given as slow IV injection or slow IM injection.
Precautions for Use
Never administer by IV infusion.
Do not use water for injection for reconstitution of the artesunate powder. Use the ampoules of diluents provided.
Storage
- Below 25°C - Protect from sunlight
- After reconstitution, use the solution immediately.