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ARTESUNATE 60mg, pwd vial + ARGININE 2%/NaHCO3 0.84% 3ml amp

https://medicalguidelines.msf.org/en/node/745
https://unicat.msf.org/cat/product/92766
NST DINJARTS6V3

Valid Article

Former Code(s): DINJARTS6V7
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
6.5.3.1 - For curative treatment
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
P01BE03
Anatomical Therapeutic Chemical Classification according to WHOCC
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

This combination does not exist.

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ARTESUNATE + ARGININE

Therapeutic Action

Antimalarial, artemisinine derivative

Indications

Severe malaria caused by Plasmodium falciparum

Instructions for use

Combi-pack including:

  • 1 powder vial containing 60 mg of artesunate
  • 1 ampoule with 3 ml of 0.84% (8.4 mg/ml) sodium bicarbonate (NaHCO3) + 2% (20 mg/ml) arginine for reconstitution

This new formulation of artesunate eliminates the need for separate reconstitution and dilution of the powder. It simplifies and speeds up administration, reducing the risk of preparation errors.

For instructions on reconstitution and administration, refer to Injectable artesunate FOR SEVERE MALARIA ONLY (see related articles).

ARTESUNATE 60mg, powder,vial + NaHCO3 5% 1ml + NaCl 0.9% 5ml (DINJARTS6V-) and ARTESUNATE 60mg, pwd vial + ARGININE 2%/NaHCO3 0.84% 3ml (DINJARTS6V3) are interchangeable, with the same weight-based dosing. Missions should gradually shift from DINJARTS6V- to DINJARTS6V3.

Must be given as a slow IV or IM injection.

Precautions for Use

Never administer by IV infusion.

Do not use water for injection to reconstitute the artesunate powder. Use the diluents contained in the 3 ml ampoule provided.

Storage

  • Below 25ºC - Protect from sunlight
  • After reconstitution, use the solution immediately.
  • Do not refrigerate or freeze.