BLEOMYCIN sulfate, eq 15.000 IU base, powder, vial

STD DINJBLEO1V-

Valid Article

Former Code(s): DINJMISC114 DINJZBD0114
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
8.2.1 - Cytotoxic medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
L01DC01
Anatomical Therapeutic Chemical Classification according to WHOCC
The order of this product needs to be justified and is only acceptable under certain conditions.
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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BLEOMYCIN

Therapeutic Action

Glycopeptide-antibiotic with cytotoxic activity

Indications

Kaposi's sarcoma in HIV patients, in combination with vincristine

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Instructions for use

Posology is expressed in IU and not in mg.

Must be given as IM or IV injection after reconstitution with the appropriate quantity of 0.9% NaCl.

Vincristine, another cytotoxic medicine, should be systematically ordered together with bleomycin as they have to be used in combination.

    Precautions for Use

    Contraindicated during breastfeeding.

    Cytotoxic medicine!

    • Dangerous substance for the staff handling it.
    • Cytotoxic drugs should not be handled or administered by pregnant staff members.
    • It is mandatory to train the staff and to follow the Standard Precautions during preparation, reconstitution, dispensation, stock management and disposal: wear gloves, gown with long sleeves, protective glasses, respirator, etc.

    (See introduction: Cytotoxic drugs in the MSF Supply Chain)

    Storage

    • Keep refrigerated between 2ºC and 8ºC.
    • Do not freeze.
    • Once reconstituted, use the solution immediately.
    • Any unused solution should be discarded.

    (Cf Introduction: Thermosensitive products)