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PHENYTOIN sodium, 50mg/ml, 5ml, vial

https://medicalguidelines.msf.org/en/node/914
https://unicat.msf.org/cat/product/11783
STD DINJPHEY2V-

Valid Article

The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
5.1 - Antiseizure medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
N03AB02
Anatomical Therapeutic Chemical Classification according to WHOCC
M
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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PHENYTOIN

This product is not always available at supply level. In this case an alternative can be found. Contact your pharmacist referent for more information.

Therapeutic Action

Antiepileptic

Indications

Phenytoin is no longer first-line treatment in the management of convulsive status epilepticus. It is replaced by either phenobarbital, levetiracetam or and sodium valproate.

Contact your OC advisor for the treatment protocol.

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Instructions for use

Must be given as slow IV infusion in 0.9% NaCl using a filter for IV line.

The solution must be clear and free of particles.

Continuous monitoring of the ECG and blood pressure is essential. Cardiac resuscitative equipment should be available.

Phenytoin can be used as an alternative to Leviteracetam, phenobarbital or sodium valproate in case of supply constraints.

Vials and ampoules are interchangeable according the availability when ordering.

Precautions for Use

Do not dilute in glucose (risk of precipitation).

Never administer by IM route.

Storage

  • Below 25ºC - Protect from sunlight
  • After dilution, use the solution immediately.
  • Discard any unused remaining solution.