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VINCRISTINE sulfate, 1mg/ml, 1ml, vial

https://unicat.msf.org/cat/product/11820
STD DINJVINC1V-

Valid Article

Former Code(s): -X
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
8.2.1 - Cytotoxic medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
L01CA02
Anatomical Therapeutic Chemical Classification according to WHOCC
P
The order of this product needs to be justified and is only acceptable under certain conditions.
0208
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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VINCRISTINE

Therapeutic Action

Antimitotic cytotoxic medicine

Indications

Treatment of Kaposi's sarcoma in HIV patients, in combination with bleomycine

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Instructions for use

Must only be given as IV infusion in 0.9% NaCl or 5% dextrose.

Ensure that the IV catheter is properly positioned in the vein before injection of vincristine. Leakage into surrounding tissue during administration may cause severe pain and severe local tissue irritation.

Purge the vein after administration of vincristine to prevent vessel irritation.

The two presentations (1 or 2 ml) are interchangeable according to availability when ordering.

Bleomycin, another cytotoxic medicine, should be systematically ordered together with vincristine as they have to be used in combination.

Precautions for Use

Administer by IV route only, fatal if given by other routes.

Contraindicated during pregnancy and breastfeeding.

Cytotoxic medicine!

  • Dangerous substance for the staff handling it.
  • Cytotoxic drugs should not be handled or administered by pregnant staff members.
  • It is mandatory to train the staff and to follow the Standard Precautions during preparation, reconstitution, dispensation, stock management and disposal: wear gloves, gown with long sleeves, protective glasses, respirator, etc.

(See introduction: Cytotoxic drugs in the MSF Supply Chain)

Storage

  • Keep refrigerated between 2ºC and 8ºC - Protect from sunlight
  • Do not freeze.
  • After dilution, use the solution immediately.

(Cf Introduction: Thermosensitive products)