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ISOFLURANE, inhalation vapour, liquid, 250ml, bot.

https://unicat.msf.org/cat/product/12095
STD DORAISOF2L-

Valid Article

Former Code(s): -X
1.1.1 - Inhalation medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
N01AB06
Anatomical Therapeutic Chemical Classification according to WHOCC
UN3334
Hazardous materials and products (identified by their 4-digit transport UN-number) must be transported under certain conditions as specified in the MSDS sheet (Material Safety Data Sheet).
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ISOFLURANE

Therapeutic Action

General inhalation anaesthetic

Halogenated methyl isopropyl ether inhalational anaesthetic which produces a rapid induction and recovery phase from anaesthesia.

Indications

Maintenance of general anaesthesia by inhalation

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Instructions for use

Isoflurane is the first choice inhalation anaesthetic. Isoflurane is not suitable for induction of anaesthesia (airway-irritant).

Sevoflurane is the second choice inhalation anaesthetic as it is more expensive than Isoflurane. Sevoflurane is less soluble than isoflurane and is therefore suitable for the induction of anaesthesia in children.

Both isoflurane and sevoflurane are suitable for day care anaesthesia. Sevoflurane has little advantages of less airway hyper reactivity and quicker emergence and discharge from Post-Anesthesia Care Unit (PACU).

The choice between inhalation agents should take into account the characteristics of the project: patients, types of procedures, available medical equipment, staff training and other factors. Contact your anaesthesia advisor for more information.

Isoflurane must only be administered by persons trained in the
administration of general anaesthesia.

Facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available.

To be used with the appropriate vaporiser and anaesthetic circuit/machine.

Portable anaesthesia system Diamedica: DPA-2 & Glostavent Helix

  • The Diamedica vaporiser can be used with both soflurane and sevoflurane.
  • The scale of the vaporiser must be correctly calibrated from the start: according to the inhalation agent used (Halothane or Isoflurane).
  • Isoflurane and sevoflurane should never be mixed and the vessels (DPA) should be clearly identified: indicate the gas used on the vessel name.
  • Contact your biomedical or anaesthesia advisor at the time of switching for specific manufacturer instructions.
  • Follow the procedures carefully.

Precautions for Use

Isoflurane may trigger a potentially lethal malignant hyperthermia in susceptible individuals.

Transport Dangerous Goods

UN transport code:

  • UN 3334 - Aviation regulated liquid n.o.s.
  • Transport Class 9 - Miscellaneous dangerous substances and articles
  • Packing group III - Substances and preparations presenting a relatively low toxicity hazard
  • Proper shipping name: Aviation regulated liquid n.o.s.
  • Not subject to International Carriage of Dangerous Goods by Rail (ADR), by road (RID) or Maritime Code (IMDG)

Storage

  • Store between 15ªC and 30°C in a cool, well-ventilated place.
  • Keep bottle tightly closed.
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H315Causes skin irritation
H319Causes serious eye irritation
H336May cause drowsiness or dizziness