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SEVOFLURANE, inhalation vapour, liquid, 250ml, bot.

https://unicat.msf.org/cat/product/66462
STD DORASEVO2L-

Valid Article

Former Code(s): DORAOCBZLB0012 DORAZFR0595
1.1.1 - Inhalation medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
N01AB08
Anatomical Therapeutic Chemical Classification according to WHOCC
SM
The order of this product needs to be justified and is only acceptable under certain conditions.
UN3334
Hazardous materials and products (identified by their 4-digit transport UN-number) must be transported under certain conditions as specified in the MSDS sheet (Material Safety Data Sheet).
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)
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SEVOFLURANE

Therapeutic Action

General inhalation anaesthetic

Halogenated methyl isopropyl ether inhalational anaesthetic which produces a rapid induction and recovery phase from anaesthesia.

Indications

Induction and maintenance of general anaesthesia by inhalation

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Instructions for use

Isoflurane is the first-choice inhalation anaesthetic but is not suitable for anaesthesia induction due to its airway-irritant properties.

Sevoflurane is the second-choice inhalation anaesthetic as it is more expensive than Isoflurane. It is less soluble than isoflurane, making it more suitable for the induction of anaesthesia in children.

Both Isoflurane and Sevoflurane are suitable for day-care anaesthesia. Sevoflurane offers advantages such as reduced airway hyper reactivity and faster emergence, which allows for quicker discharge from the Post-Anesthesia Care Unit (PACU).

The choice between inhalation agents should consider the characteristics of the project: patients, procedures types, available medical equipment, staff training, and other factors. Contact your anaesthesia advisor for more information.

Sevoflurane must only be administered by persons trained in the administration of general anaesthesia.

Ensure that facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation are immediately available.

To be used with the appropriate vaporiser and anaesthetic circuit/machine.

Portable anaesthesia system Diamedica: DPA-2 & Glostavent Helix

  • The Diamedica vaporiser can be used with both sevoflurane and isoflurane.
  • Sevoflurane should be administered with a vaporiser calibrated specifically for sevoflurane (EANEANAA501).
  • The vaporiser scale must be calibrated correctly from the start, based: on the inhalation agent being used (Sevoflurane or Isoflurane).
  • Sevoflurane and isoflurane should never be mixed. Ensure that the vessels (DPA) are clearly identified, indicating the gas in use.
  • Contact your biomedical or anaesthesia advisor when switching agents for manufacturer specific instructions.
  • Follow all procedures carefully.

Precautions for Use

Sevoflurane may trigger potentially lethal Malignant Hyperthermia in susceptible individuals.

Transport Dangerous Goods

UN transport code:

  • UN 3334 - Aviation regulated liquid n.o.s.
  • Transport Class 9 - Miscellaneous dangerous substances and articles
  • Packing group III - Substances and preparations presenting a relatively low toxicity hazard
  • Proper shipping name: Aviation regulated liquid n.o.s.
  • Not subject to International Carriage of Dangerous Goods by Rail (ADR), by road (RID) or Maritime Code (IMDG)

Storage

  • Store between 15ªC and 30°C in a cool, well-ventilated place.
  • Keep bottle tightly closed.
Image
H315Causes skin irritation
H319Causes serious eye irritation
H336May cause drowsiness or dizziness