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CAPREOMYCIN sulfate, powder, 1 g [Sigma-C4142-1G]

https://medicalguidelines.msf.org/en/node/1123
https://unicat.msf.org/cat/product/18751
NST SASTAPWDCAP1

Valid Article

Former Code(s): SLASCAPR1P- SLASMISC081 SLASZNL0081 SLASMISC281 SLASZFR0281
Single use
A single-use device, also referred to as a disposable device, is intended for use on one patient during a single procedure. It is not intended to be reprocessed (i.e., cleaned and disinfected or sterilized).
W0104010699 - Media for mycobacteria cultures - manual & automated (for ast drugs , supplements) - other
European Medical Device Nomenclature (EMDN) is the nomenclature of use by manufacturers when registering their medical devices in the EUDAMED database. EMDN is characterised by its alphanumeric structure that is established in a seven-level hierarchical tree.
P
The order of this product needs to be justified and is only acceptable under certain conditions.
FSRT
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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CAPREOMYCIN sulfate, powder

Article NST in 2021 - No longer part of the drug susceptibility testing of M. tuberculosis complex.

Reserved for TB culture programmes.

Definition

Antimycobacterial used for drug susceptibility testing of M. tuberculosis complex.

Synonym

Capreomycin sulfate, from Streptomuces capreolus

Specifications

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Technical specifications

  • Powder
  • White to off-white, in solution colourless to faint yellow
  • Soluble in water
  • Formula : C24H44N14O12​S
  • CAS n° 1405-37-4

Packaging & Labelling

1 g in glass vial

Transport not regulated

Instructions for use

  • For the preparation of stock solutions and working solutions, refer to Tuberculosis Culture Laboratory, MSF-ITM, 2014.
  • The drug working solution is added to the medium during preparation (agar or LJ) or prior to inoculation (MGIT broth tubes).

Storage

  • Recommended storage temperature: -20°C
  • Keep container tightly closed in a dry and well-ventilated place
  • Avoid exposure and formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
  • Shelf life: 24 months
  • Transport in cold chain conditions
  • DEEP FREEZE storage at reception

(Cf Introduction: Thermosensitive products)

Classification EC Regulation N° 1272/2008

  • Acute toxicity, Inhalation: Category 4, H332
  • Acute toxicity, Dermal, Category 4, H312
  • Acute toxicity, Oral, Category 4, H302
  • Reproductive toxicity, Category 1B, H360
Image Image

Signal Word

Danger

H302Harmful if swallowed
H312Harmful in contact with skin.
H332Harmful if inhaled.
H360May damage fertility or the unborn child (state specific effect if known) (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)
P201Obtain special instructions before use.
P280Wear protective gloves/protective clothing/eye protection/face protection
P308 + P313IF exposed or concerned: Get medical advice/attention.

MSF requirements

Capreomycin is part of the second line drugs used against M. tuberculosis complex. The test is performed to investigate resistance of the mycobacteria to this antibiotic. It can be used for liquid and solid cultures.

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