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MANNITOL, 20%, 500ml, flex. bag, PVC free

https://unicat.msf.org/cat/product/71530
STD DINFMANN2FBF5

Valid Article

The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
16 - Diuretics
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
B05BC01
Anatomical Therapeutic Chemical Classification according to WHOCC
PM
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)
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MANNITOL 20%

Therapeutic Action

Osmotic diuretic

Indications

Increased intracranial pressure in patients with traumatic brain injury

Cerebral oedema

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Instructions for use

Must be given as slow IV infusion.

Never administer by IM or SC route.

Use a filter for IV line because of the risk of crystal formation with mannitol.

Precautions for Use

Contraindicated in patients with abnormal capillary fragility, pulmonary congestion or pulmonary oedema, intracranial bleeding, congestive heart failure, or renal failure - unless a test dose has demonstrated a diuretic response.

Remark

Mannitol is a saturated solution and may occasionally crystallise:

  • Do not administer if the solution contains crystals.
  • Inspect the solution carefully for crystals immediately before use.
  • If crystals are observed, redissolve them by heating the solution to 60°C in a water bath, shaking regularly until fully dissolved.
  • Keep the bottle upright in the water bath; do not immerse the top in water.
  • Do not use a microwave to heat the solution.
  • Allow the solution to cool to room temperature before administration.

In case of local purchase, flexible bags are preferred to semi-rigid bottles. Contact your OC pharmacist for validation and approval.

Storage

  • Bellow 25ºC.
  • Do not refrigerate.
  • Do not freeze.
  • After opening, use the product immediately.

Caution!

It is important to pay attention to stack-piling, handling and internal transport conditions to prevent compression of the secondary packaging, which could lead to micro-leakage of the bottle or bag (risk of microbial contamination).

See Preliminary remarks on infusions