ENOXAPARIN sodium, 4,000 IU/0.4ml, syr.
STD
DINJENOX40S
Valid Article
HS Code:
300490
Last Updated on:
31/07/2024, 22:03:16
Former
Code(s):
DINJENOX2S- DINJMISC153 DINJZFR0153
10.2 - Medicines affecting coagulation
Classification of the medicines in groups and subgroups according to their therapeutic use.
The classification used by MSF is based on the WHO Model List of Essential Medicines.
B01AB05
Anatomical Therapeutic Chemical Classification according to WHOCC
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
ENOXAPARIN
Exnoxaparin replaces nadroparin (non-standard due to supply constraints). Dosage should be adapted accordingly.
Therapeutic Action
Anticoagulant, low molecular weight heparin (LMWH)
Indications
Prevention and treatment of venous thromboembolic disease in adults
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Instructions for use
Pre-filled syringe at :
- 10,000 IU = 100 mg enoxaparin sodium in 1 ml WPI
- 2,000 IU = 20 mg enoxaparin sodium in 0.2 ml WPI
- 4,000 IU = 40 mg enoxaparin sodium in 0.4 ml WPI
- 6,000 IU = 60 mg enoxaparin sodium in 0.6 ml WPI
Equivalences:
- Enoxaparin 0.2 ml (2000 UI) = Nadroparin 0.3 ml (2850 UI)
- Enoxaparin 0.4 ml (4000 UI) = Nadroparin 0.4 ml (3800 UI)
- Enoxaparin 0.6 ml (6000 UI) = Nadroparin 0.6 ml (5700 UI)
Must be given as deep SC injection:
- Administer preferably with the patient in the supine position, in the subcutaneous cellular tissue of the anterolateral and posterolateral abdominal belt, alternating between the right and left sides.
- Remove the protective cap from the needle.
- Do not expel the air bubble from the syringe.
- If a drop appears at the tip of the needle, remove the drop before injection by tapping on the body of the syringe (needle pointing downwards).
- Insert the entire length of the needle perpendicularly and not tangentially, into a skin fold gently held between the thumb and index finger. Maintain the skin fold throughout the injection.
- Do not rub the injection site after administration.
- Immediately dispose of the syringe in the appropriate container. Any unused medication should be discarded.
Monitor coagulation parameters in order to adjust dose.
Check platelet counts before starting treatment and then twice a week.
Effects may be reversed by the slow IV administration of protamine, a specific heparin antagonist.
Precautions for Use
Do not administer by IM route.
Storage
- Below 25ºC
- Do not freeze.
- Pre-filled syringes are single-dose packs. Discard any unused product.