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CARBIMAZOLE, 20mg, tab.

https://unicat.msf.org/cat/product/41027
STD DORACARZ2T-

Valid Article

Former Code(s): DORAZBD0469 DORAZYN1042
18.7 - Thyroid hormones and antithyroid medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
H03BB01
Anatomical Therapeutic Chemical Classification according to WHOCC
PM
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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CARBIMAZOLE

Therapeutic Action

Inhibition of production of thyroid hormones

Carbimazole is a pro-drug that is converted into the active form, methimazole, after absorption. Methimazole inhibits the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin. This process reduces the production of the thyroid hormones T3 and T4 (thyroxine).

Indications

Hyperthyroidism

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Instructions for use

It should only be used if regular laboratory monitoring of thyroid function is available.

Precautions for Use

Do not administer during the first trimester of pregnancy.

Contraindication: severe blood disorders

Stop immediately the administration if there is clinical or laboratory evidence of
neutropenia.

Storage

Below 25ºC