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IPRATROPIUM bromide, 20mcg/puff, 200 puffs, aerosol

https://medicalguidelines.msf.org/en/node/421
https://unicat.msf.org/cat/product/66327
STD DORAIPRA2SF

Valid Article

Former Code(s): DORAOCBZLB0018 DORAZNL0312 DORAIPRA2S-
25.1 - Antiasthmatic medicines and medicines for chronic obstructive pulmonary disease
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
R03BB01
Anatomical Therapeutic Chemical Classification according to WHOCC
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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IPRATROPIUM aerosol

Therapeutic Action

Inhaled anticholinergic bronchodilator.

After inhalation, it causes rapid bronchodilation within minutes (approx. 3 min.) and lasting for 4-6 hours.

Indications

Control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD) in combination with inhaled salbutamol or salmeterol.

Acute management of severe asthma exacerbation in combination with inhaled salbutamol.

Instructions for use

Suspension or solution in a pressurised metered-dose inhaler: small canister containing a mixture of medicine and pressurised propellant. The pressure from the propellant delivers the medicine from the canister when the canister is pushed down into the boot/actuator.

Method of administration:

  • Shake the inhaler and ensure that liquid is heard. Remove the mouthpiece cover.
  • Inhale and then exhale as completely as possible.
  • Place the lips firmly around the mouthpiece..
  • Start to inhale with a long, slow breath and continue to breath as deeply as possible when activating the inhaler (puff).
  • Remove the inhaler, close the lips and hold the breath for 10 seconds, or as long as is comfortable.
  • Exhale, wait a few seconds, shake the inhaler again and repeat for the next puff, if required.

Manufacturers may express the content per puff as a "metered dose" (excluding the valve, i.e the quantity of drug substance contained in the device metering chamber) or as a "delivered dose" (excluding the mouthpiece, i.e. the quantity of drug substance delivered to the user). Always consult the product leaflet.

Refer to the information leaflet for appropriate instructions for use/inhalation according the inhaler model.

Pressurised metered-dose inhalers are CFC free presentation. Chlorofluorocarbons (CFCs) are harmful to the ozone layer and HFA (hydrofluoroalkane) propellant is a more effective, and environmentally-friendly alternative.

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Precautions for Use

Use in combination with inhaled salbutamol.

In children, use an inhalation chamber/spacer with or without a mask (depending on the age of the child) with every administration of pressurised metered-dose inhalers.

In patients who have difficulty coordinating the actuation on the metered-dose inhaler and inhalation (e.g elderly patients), use an inhalation chamber/spacer to facilitate administration and improve the effectiveness of the product.

Do not use any mouthpiece other than the one supplied with the inhaler.

Transport Dangerous Goods

UN transport code:

  • UN 1950 - Aerosols, non-flammable (each not exceeding 1 L capacity)
  • Transport Class 2.2 - Non-flammable, non-toxic gases

Transport is only regulated for large quantities of aerosols.

Storage

  • Below 25ºC - Protect from sunlight
  • Used aerosols: do not pierce or incinerate. Empty all residual gas, then bury.
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