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VECURONIUM bromide, 10mg, powder, vial

https://unicat.msf.org/cat/product/68797
STD DINJVECB1V-

Valid Article

The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
20 - Muscle relaxants (peripherally-acting) and cholinesterase inhibitors
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
M03AC03
Anatomical Therapeutic Chemical Classification according to WHOCC
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
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VECURONIUM

Therapeutic Action

Neuromuscular blocking agent (NMBA), non-depolarising, with an intermediate onset and duration of action.

Indications

Maintenance of neuromuscular block during surgery.

In critical care, NMBAs are used in specific indications: intubation, mechanical ventilation of ARDS acute respiratory distress syndrome, acute asthma exacerbation, tetanus.

Vecuronium is considered as second choice non-depolarizing NMBA. It can be used an an alternative to rocuronium (first-choice non-depolarizing NMBA) in case of supply issue or import constraints with rocuronium.

Instructions for use

Reconstitute the powder vial with 5 ml of water for injection.

The reconstituted solution must be given as IV injection (bolus) or continuous IV infusion.

Systematically order neostigmine together with vecuronium.

Systematically order the corresponding pre-printed label to identify the syringe containing the product.

Rocuronium has a better profile than vecuronium as it allows to be used in the two scenarios : induction in rapid sequence and maintenance of neuromuscular block.

Precautions for Use

Vecuronium solution is not compatible with thiopental solution. Flush the tube before injecting vecuronium.

Caution concerning neuromuscular blocking agents (NMBAs)!

  • NMBAs are high-risk medications: paralysing agent that may cause respiratory distress.
  • NMBAs must only be administered in environments with equipment and monitoring for advanced airway respiratory support.
  • Syringes containing a NMBA must be identified with a standard pre-printed label corresponding to the product.
  • If not needed, the NMBA must be disposed accordingly.

Storage

  • Below 25ºC
  • After reconstitution, use the solution immediately.
  • Discard any unused solution.