HYDROXYCARBAMIDE, 500mg, caps.
Valid Article
HYDROXYCARBAMIDE
Full Name
Hydroxycarbamide (Hydroxyurea)
- In the WHO list of Essential Medicines 2023 (Complementary List)
Therapeutic Action
Antineoplastic antimetabolite increasing the production of foetal haemoglobin, which decreases the sickling of erythrocytes, reducing the frequency of painful crisis and the need for blood transfusions in sickle cell patients.
Indications
Prevention of recurrent painful vaso-occlusive crises, including acute chest syndrome in adults, adolescents, and children over 2 years of age with symptomatic Sickle Cell Syndrome.
Instructions for use
Precautions for Use
Contraindicated in case of severe anaemia.
Monitor closely the haematological status, renal and hepatic functions.
Administer with caution in patients with mild to moderate renal impairment.
Storage
Below 25°C - Protect from sunlight - Protect from humidity