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ARTESUNATE 60mg, powder,vial +NaHCO3 5% 1ml +NaCl 0.9% 5ml

https://medicalguidelines.msf.org/en/node/745
https://unicat.msf.org/cat/product/11631
STD DINJARTS6V-

Valid Article

Former Code(s): -X
The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
6.5.3.1 - For curative treatment
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
P01BE03
Anatomical Therapeutic Chemical Classification according to WHOCC
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ARTESUNATE

Therapeutic Action

Antimalarial, artemisinine derivative

Indications

Severe malaria caused by Plasmodium falciparum

Instructions for use

Combi-pack containing two necessary diluents:

  • 1 powder vial of 60 mg artesunate
  • 1 ampoule containing 1 ml of 5% sodium bicarbonate (NaHCO3) for reconstitution
  • 1 ampoule containing 5 ml of 0.9% NaCl for dilution

Refer to the instructions detailed in GUIDELINES FOR ADMINISTRATION OF INJECTABLE ARTESUNATE FOR SEVERE MALARIA (see articles related) for reconstitution, dilution and administration.

ARTESUNATE 60mg, powder,vial + NaHCO3 5% 1ml + NaCl 0.9% 5ml (DINJARTS6V-) and ARTESUNATE 60mg, pwd vial + ARGININE 2%/NaHCO3 0.84% 3ml (DINJARTS6V3) are interchangeable and weight-dosing is the same. Missions should progressively shift from DINJARTS6V- to DINJARTS6V3.

Must be given as slow IV injection or slow IM injection.

Precautions for Use

Never administer by IV infusion.

Do not use water for injection for reconstitution of the artesunate powder. Use the ampoules of diluents provided.

Storage

  • Below 25°C - Protect from sunlight
  • After reconstitution, use the solution immediately.