ATRACURIUM besilate, 10mg/ml, 2.5ml, amp.
Valid Article
ATRACURIUM besilate
- In the WHO list of Essential Medicines 2023 (Therapeutic alternative to vecuronium)
Therapeutic Action
Neuromuscular blocking agent (NMBA), non-depolarising, with an intermediate onset and duration of action.
Indications
Maintenance of neuromuscular block during surgery.
In critical care, NMBAs are used in specific indications: intubation, mechanical ventilation of ARDS acute respiratory distress syndrome, acute asthma exacerbation, tetanus.
Atracurium can be considered as second choice non-depolarizing NMBA in projects where there is a substantial medical need to account for hepatic or kidney function.
Instructions for use
Must be given as IV injection or continuous IV infusion.
Systematically order neostigmine together with atracurium.
Systematically order the corresponding pre-printed label to identify the syringe containing the product.
Atracurium can be used as an alternative to vecuronium, when vecuronium cannot be imported or used.
Precautions for Use
Atracurium requires cold chain for transport and storage, it is essential to ensure that a properly functioning cold chain is in place before ordering.
Caution concerning neuromuscular blocking agents (NMBAs)!
- NMBAs are high-risk medications: paralysing agent that may cause respiratory distress.
- NMBAs must only be administered in environments with equipment and monitoring for advanced airway respiratory support.
- Syringes containing a NMBA must be identified with a standard pre-printed label corresponding to the product.
- If not needed, the NMBA must be disposed accordingly.
Storage
- Between 2ºC and 8ºC - Protect from sunlight
- Do not freeze.
- After opening the ampoule, use the product immediately.
- Discard any unused solution.